Objective: To present the current understanding of normal anatomy, physiology, sexual physiology, pathophysiology and the consequential sexual changes and dysfunctions following a spinal cord injury SCI. Methods: Narrative review of the latest literature. Results: Peripheral innervations of the pelvis involve 3 sets of efferent neurons coordinated though the pelvic plexus somatic, thoracolumbar sympathetic, and sacral parasympathetic , and these are under cerebral descending excitatory and inhibitory control. SCI, depending on the level of lesion and completeness, can alter this cerebral control, affecting the psychological and reflexogenic potential for genital arousal and also ejaculation and orgasm.

AACC uses Cookies to ensure the best website experience. Continuing without changing Cookie settings assumes you consent to our use of cookies on this device. You can change these settings at any time, but that may impair functionality on our websites. Review our cookie and privacy policy. Costly and invasive tissue biopsies to detect allograft rejection after transplantation have numerous limitations.

Being knowledgeable about anatomy and physiology increases our potential for pleasure, physical and psychological health, and life satisfaction. Beyond personal curiosity, thoughtful discussions about anatomy and physiology with sexual partners reduces the potential for miscommunication, unintended pregnancies, sexually transmitted infections, and sexual dysfunctions. Lastly, and most importantly, an appreciation of both the biological and psychological motivating forces behind sexual curiosity, desire, and the capacities of our brains can enhance the health of relationships. Most people are curious about sex.

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